Views: 504 Author: Site Editor Publish Time: 2024-07-11 Origin: Site
In the field of life sciences and molecular biology, thermocyler is an indispensable key instrument, which is widely used in experimental processes such as polymerase chain reaction (PCR). The performance of the thermocyler plays a crucial role in the accuracy and reliability of the experimental results, and the application of thermal conductive graphite materials provides strong support for the efficient operation and accurate temperature control of the thermocycler.
For example, a well-known brand of thermocycler, in its latest product design, uses thermal conductive graphite sheets attached between the heating module and the reaction chamber. In the actual PCR experiment, this design makes the temperature from denaturation temperature (such as 95℃) to annealing temperature (such as 55-65 ℃) compared to the previous generation of products to improve the conversion speed of 30%, greatly shortening the entire PCR reaction time, while improving the amplification efficiency. Moreover, due to the uniform thermal conductivity of the conductive graphite, the temperature difference between different reaction holes in the same batch is controlled within ±0.2℃, which ensures the high repeatability and accuracy of the experimental results.
Another example is another advanced thermocycler, which integrates thermal conductive graphite materials into the manufacture of the reaction chamber to form an integrated thermal conductive structure. The thermocycler has demonstrated excellent stability over long periods of continuous experimental operation, enabling precise temperature control, whether for high frequency rapid thermal cycles or for long periods of time maintained at a specific temperature. When the researchers used the thermocycler to conduct quantitative PCR experiments for gene expression analysis, they successfully achieved DNA detection as low as a single copy, and the coefficient of variation of the experimental results was significantly reduced, fully demonstrating the advantages of thermal graphite sheet in accurate temperature control.
The thermal graphite sheet produced by Dasen has an extremely high thermal conductivity. Compared with traditional thermal conductivity materials, such as metals, thermal graphite sheet has better thermal conductivity. This means that when the thermocycler is working, the thermal conductive graphite can quickly transfer heat from the heating element to the reaction chamber, or when it is necessary to cool down, the heat is quickly exported from the reaction chamber, which greatly reduces the response time of temperature changes and improves the efficiency of the thermal cycle.
In addition, the conductive graphite also has good thermal uniformity. In the reaction chamber of the thermocycler, the uniform distribution of temperature is essential to ensure the consistency and repeatability of the PCR reaction. Thermal conductive graphite can evenly spread heat to the entire reaction area, so that the temperature of each reaction site remains highly consistent, reducing the experimental error caused by temperature differences, thus improving the accuracy and reliability of experimental results.
In addition to excellent thermal conductivity, thermal graphite sheet also has the characteristics of lightweight and thin. This makes the overall structure of the thermocycler more compact and lightweight, easy to place and operate in the laboratory, but also conducive to the portable development of the instrument.
In the course of long-term use, thermal graphite sheet also shows excellent stability and durability. It can withstand the frequent thermal cycle impact, is not easy to deformation, aging or performance decline phenomenon, to ensure the long-term stable operation of the thermal cycle instrument, reduce the maintenance cost and use risk of the instrument.
In short, the application of thermal conductive graphite in the thermocycler greatly improves the performance and function of the thermocycler, and provides strong technical support for life science research and molecular biology experiments. Thermal conductive graphite plays an important role in thermocycler and other instruments requiring accurate thermal control, if you happen to have a need for this, welcome to contact us for details!